Pulmonary inflammatory myofibroblastic tumor coexisting with lymphangitis carcinomatosis: Mimicking metastatic papillary thyroid carcinoma with nodular fasciitis-like stroma

Inflammatory myofibroblastic tumors (IMTs) are uncommon; intermediate grade soft tissue tumors occurring in young individuals with Generating User Privacy-Controllable Synthetic Data for Recommendation Systems an uncertain behaviour.The incidence of pulmonary lymphangitis carcinomatosis (PLC) is around 6-8% of all pulmonary metastases.However, PLC due to papillary thyroid carcinoma (PTC) is very uncommon.

We present a case of a 26-year-old male, who presented with a solitary left lung nodule on radiological scans.There was also a past history of thyroid surgery done two years back for PTC.Histology revealed a soft tissue tumor reminiscent of IMT.

The periphery of the IMT nodule showed metastatic PTC in the form of extensive PLC.In view of this unusual histology, a diagnosis of PTC Epidemiological Aspects and Differential Diagnosis of the Cutaneous Round Cell Tumors in Dogs with nodular fasciitis-like stroma (PTC-NFS) was initially considered.However, molecular studies for anaplastic lymphoma kinase (ALK) gene rearrangement confirmed the diagnosis of IMT.

This case highlights the unusual occurrence of tumor-to-tumor metastasis causing diagnostic challenges and also the importance of molecular testing.

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